Proteoglycan-fibrillar collagen interactions
نویسندگان
چکیده
منابع مشابه
Proteoglycan-fibrillar collagen interactions.
The future of biochemistry lies in understanding how single gene products associate and function together. Interactions in connective tissues, including those between the proteoglycans and collagens are especially piquant, evolutionarily conserved and physiologically significant. Connective tissues (e.g. skin, tendon, blood vessels, etc.) are systems of insoluble fibrils and soluble polymers wh...
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Introduction Cornea presents a deceptively simple picture. It is a transparent structure that looks much the same in all sighted animals, and throughout life; a window that helps focus light on the back of the eye. It is a typical connective tissue (the dry weight consists mainly of collagen and proteoglycans) but it also contains much water ( 80% of wet weight e.g. [ 11). In essence it is a sl...
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Collagens, or more precisely collagen-based extracellular matrices, are often considered as a metazoan hallmark. Among the collagens, fibrillar collagens are present from sponges to humans, and are involved in the formation of the well-known striated fibrils. In this review we discuss the different steps in the evolution of this protein family, from the formation of an ancestral fibrillar colla...
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The purpose of this article is to review our knowledge to date of collagen-proteoglycan interaction. Many topics have been taken into account in order to provide a reasonably complete picture of this highly complex subject. Basic information about collagen biology, and an overview of the current concepts and advances regarding proteoglycans, have served as a basis to elucidate collagen-proteogl...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1988
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2520313